• 680C91 br Material and methods br Results

  2019-09-20

  

  Material and methods Results Discussion Ligase IV is essential for the final ligation of DSBs through the NHEJ pathway. Its co-factor, XRCC4, has been shown to be important for increasing its activity and stability. Interaction between these two factors have been mapped to the linker region

• Moreover a ligand for fusin

  2019-09-20

  

  Moreover, a ligand for fusin has recently been found: the lymphocyte chemoattractant stromal-derived factor-1 (SDF-1) binds to CHO antioxidant transfected with fusin and promotes secondary messenger production (Bleul et al., 1996; Oberlin et al., 1996). A new name, CXCR-4, has been proposed for the

• It should be noted that there are other methods such

  2019-09-20

  

  It should be noted that there are other methods, such as artificial intelligence, like Artificial Neural Networks/ANN (such as PSO-ANN, ICA-ANN), Least Square Support Vector Machine/LSSVM, etc. [10], [11], [12], [13], [14], [15], [16], [17], [18], or molecular simulations, for modeling the fluid\'s

• br Materials and methods br Results br Discussion It has

  2019-09-20

  

  Materials and methods Results Discussion It has been demonstrated that up-regulation of EPHB4 impaired trophoblast migration and invasion during placentation, which may contribute to the pathogenesis of preeclampsia [11], [24]. However, the upstream regulating mechanism of EPHB4 expression

• Results are expressed as mean s e m Paired

  2019-09-20

  

  Results are expressed as mean±s.e.m. Paired or unpaired Student\'s t test was used for comparisons between 2 groups and one-way ANOVA followed by Bonferroni\'s post-test for more groups. Statistical significance was assigned if p Results and discussion Variations in [Ca2+]i in cardiomyocytes loade

• BMS 193885 br Disclosure statement br Acknowledgements This

  2019-09-20

  

  Disclosure statement Acknowledgements This research was supported by grants from the National Institutes of Health, NS046400 and AG022971 (SD), and a fellowship from the Korea Research Foundation, KRF-2007-357-E00016 (YTK). The authors thank Dr. Barbara Crain for assistance with the immunologi

• Linezolid Key molecules in the EP second messenger signaling

  2019-09-20

  

  Key molecules in the EP1 second messenger signaling cascade that are necessary for potentiation of GluK2/GluK5 were identified. We also identified three GluK5 serines located in a membrane-proximal C-terminal domain that, when mutated to the phosphomimetic aspartate and expressed with GluK2, rendere

• br Materials and Methods br Results br Discussion HSCs have

  2019-09-19

  

  Materials and Methods Results Discussion HSCs have been identified as major collagen-producing GSK2194069 in the injured liver (1), and activation of HSCs has become the central link for liver fibrosis (2). The factors that regulate the biological behavior of HSCs include soluble regulatory

• Keratin K has been identified as the first

  2019-09-19

  

  Keratin 8 (K8) has been identified as the first intermediate filament expressed during development in amphibians and mammals. In zebrafish, a type II cytokeratin 8 (zf-K8) cDNA has been cloned. zf-K8 gene was maternally inherited and expressed in all surface cells throughout the embryonic stages old

• br Preparation of Recombinant Proteins br Activity Assays Th

  2019-09-19

  

  Preparation of Recombinant Proteins Activity Assays The following solvents are used in the procedures described in this section: Data Analysis Aryl radical rearrangements typically result in a large number of products being generated by Bmp7. Approaches combining mass spectrometry and NMR

• Apart from its high affinity

  2019-09-19

  

  Apart from its high affinity, the selection of GW2580 as Floxuridine mass lead in our radiotracer development program was motivated by its exceptional selectivity. The observed profound impact of small structural modifications on the selected panel of four kinases tested prompted us to conduct compr

• In solid tumors such as those in breast

  2019-09-19

  

  In solid tumors, such as those in breast and pancreatic cancer, infiltrating CD68+ or CD163+ tumor-associated macrophages (TAMs) correlate with poor outcome (DeNardo et al., 2011, Kurahara et al., 2011, Shabo et al., 2008). The tumor-promoting function of TAMs is based on their capacity to secrete p

• For reductive amination by L AmDH the term related to

  2019-09-19

  

  For reductive amination by L-AmDH, the term related to the enzyme-ammonia complex is excluded rather than the enzyme-pentanone term (Table 1). If this were an ordered mechanism, this would imply ammonia binds second, after NADH and before 2-pentanone. However, a large KM,NH4 value renders ammonia bi

• br Materials and methods br

  2019-09-19

  

  Materials and methods Results Discussion To our knowledge, this is the first large-scale longitudinal measurement of more than 20 cytokines in normal pregnancy. Simultaneous measurements of several cytokines with multiplex magnetic bead-based immunoassays are becoming increasingly common in

• ApicomplexansApicomplexans are unicellular and spore forming

  2019-09-18

  

  ApicomplexansApicomplexans are unicellular and spore-forming obligate intracellular parasites that occupy diverse host niches (Mogi and Kita 2010). They have remodeled mitochondrial carbon and energy metabolism through reductive evolution. The development of novel drugs is now a very serious challe

15954 records 983/1064 page Previous Next First page 上5页 981982983984985 下5页 Last page