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br Materials and methods br Results
2021-02-10

Materials and methods Results Discussion This study is the first to our knowledge that describes upstream cis-elements and transcription factors that are important for Crm1 expression and that drive its high expression in cancer and transformed cells. Using deletion and mutation analysis we
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br Objectives br Study design Thirty KTx http www
2021-02-10

Objectives Study design Thirty KTx recipients were enrolled in this pilot study from December 2015 to May 2016. Patient demographics are presented in Table 1. The inclusion criteria were: age ≥ 18 years and CMV-IgG serostatus (D+/R−, D+/R+, D−/R+) pre-Tx. All patients were enrolled during the
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The acetylcholinesterasic activity of exposed animals after
2021-02-10

The acetylcholinesterasic activity of exposed animals, after treatment with diverse concentrations of uranium and following distinct recovery periods, remained unaltered for all species. This finding suggests that uranium, in spite of being a water-soluble metal, does not exert any effect on the sel
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Dose response analysis Fig can be performed
2021-02-09

Dose response analysis (Fig. 2) can be performed on thyrotropin releasing hormone in culture, in tissue, in animals or even in patients. Many different responses can be measured, including mRNA levels, reporter gene activity, gene product (e.g. enzyme) activity or even physiological functions such
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br Nuclear estrogen receptors Indirect
2021-02-09

Nuclear estrogen receptors: Indirect genomic signaling As mentioned earlier, the transcription of several genes that do not contain EREs in their promoter regions can also be regulated by estradiol, without direct binding of the estrogen receptors to the DNA. According to the most recent reports,
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Being a rare renal tumor its description as
2021-02-09

Being a rare renal tumor, its description as primary renal tumor has been confined to the documentation of anecdotal case reports in the past [4], [9], [10], [11]. However, recent years have seen an increased interest in defining ES/PNET of kidney as a distinct entity, with the study undertaken by t
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EphB promotes tumor growth by stimulating angiogenesis
2021-02-09

EphB4 promotes tumor growth by stimulating angiogenesis through EphrinB2 [18]. However, the distinct and specifically involvement of wnt signaling pathway and veins in the tumor angiogenesis of all tumor grades is unclear. Our results indicate that the relation between EphrinB2 and EphB4 stained bl
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To understand the behavior of enzymes in ILs at a
2021-02-09

To understand the behavior of enzymes in ILs at a molecular level, it is first desirable to dissolve enzymes in the solvents. For soluble catalysts, there are many relatively simple spectroscopic and other techniques for obtaining accurate information at a molecular level. Parker et al. [9] reported
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br Conclusions In conclusion the substrates c e
2021-02-09

Conclusions In conclusion, the substrates 18c–18e all produced highly fluorescent colonies with the panel of Gram-negative microorganisms. This has been attributed to the combination of two synergistic effects; the wide distribution of l-alanylaminopeptidase in Gram-negative microorganisms and th
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dabigatran etexilate Recoverin is a kDa retinal protein that
2021-02-09

Recoverin is a 23-kDa retinal protein that binds to calcium. It regulates the dabigatran etexilate of rhodopsin during visual transduction within photoreceptor cells. Since the pathogenicity of anti-recoverin antibody is potent, anti-recoverin CAR patients often have progressive visual impairments,
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According to the Nomenclature Committee of the International
2021-02-09

According to the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB, 1992), peptidases are divided into two classes, namely exopeptidases and endopeptidases, based on their actions on substrates and their active sites, respectively. Endopeptidases inclu
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br Introduction In mammals there are ten known isoforms of
2021-02-09

Introduction In mammals there are ten known isoforms of the enzyme diacylglycerol kinase (DGK), as well as gene splice variants. Enzymes of this family all have a homologous active site but differ widely in their molecular mass, mechanisms of activation and biological function (Shulga et al., 201
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house Some pyrimidine analogs are substrate
2021-02-09

Some pyrimidine analogs are substrate-based inhibitors that bind to the dihydroorotate binding site, but most reported inhibitors of DHODH bind to the site occupied by the ubiquinone co-factor., , , , , , , , , , , , , , , , , X-ray crystallographic studies of inhibitor complexes with DHODH and DHO
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In conclusion by investigating the cysteine protease transcr
2021-02-09

In conclusion, by investigating the cysteine protease transcriptome in soybean nodules, we found a number of cysteine proteases belonging to the C1 and C13 families strongly up-regulated following drought exposure such as C1 cysteine protease Glyma.14G085800 and C13 cysteine proteases Glyma.17G23070
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br Acknowledgement This research was supported
2021-02-09

Acknowledgement This research was supported by a grant from the National Research Foundation of Korea (NRF-2013R1A1A2011238) funded to Young-Mi Lee. Introduction Stroke is considered a serious disease with high morbidity and high mortality. More than 6 million deaths are reported each year wo
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