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LPA binds to six specific
2023-09-23
LPA binds to six specific cell surface GPCR receptors. The receptors LPA1 (lysophosphatidic receptor 1, formerly, Edg2), LPA2 (Edg4) and LPA3 (Edg7) belong to the endothelial differentiation gene family (EDG) and share sequence homology (50–60% amino jak inhibitors homology) An et al., 1997, An et a
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Amsacrine In a study highlighted the usefulness of arginase
2023-09-23
In 2010, a study highlighted the usefulness of arginase-1 as a sensitive and specific marker of hepatocytic differentiation for diagnostic pathology [9]. Subsequent studies have validated the high sensitivity and specificity of arginase-1, in particular its added value in evaluating poorly different
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br Results br Discussion AP a heterodimeric
2023-09-23
Results Discussion AP-1, a heterodimeric transcription factor comprising various combinations of FOS, JUN, MAF, ATF, and CREB family proteins, has been known to play a pivotal role in leukocyte development for decades (Liebermann et al., 1998; Valledor et al., 1998). However, its participation
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Bamboo shoots with their high nutritive http www apexbt com
2023-09-23
Bamboo shoots, with their high nutritive and therapeutic value, are now used for food fortification (Nirmala & Bisht, 2017). Several value-added products such as nuggets, crackers, chutney, snacks, cookies, cakes, chappaties, and buns have been prepared from bamboo shoots (Table 3). Dietary fiber fr
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Introduction Antimicrobial resistance is a growing health th
2023-09-23
Introduction Antimicrobial resistance is a growing health threat worldwide that has been associated with incorrect prescription and overuse of GW311616 hydrochloride [1]. Considering that physicians play a central role in antibiotic usage, a better understanding of their prescribing behaviours and
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MDV 3100 br AR expression in breast tissue Although androgen
2023-09-23
AR expression in breast tissue Although androgenic signalling is chiefly associated with the development and maintenance of primary and secondary male characteristics, especially during puberty when the testes are by far the major source of testosterone, the AR also plays important functions in f
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br Conclusions In sum enhanced incentive motivation
2023-09-23
Conclusions In sum, enhanced incentive motivation in obesity-prone rats is mediated by NAc CP-AMPARs. These neurobehavioral differences may render obesity-susceptible populations more sensitive to the motivational influence of food cues, producing more intense, focused, “wanting” that may limit t
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br Acknowledgments This work was supported by
2023-09-23
Acknowledgments This work was supported by a grant of the Romanian National Authority for Scientific Research, CNCS – UEFISCDI, project no. PN-II-ID-PCE-2011-3-0571, awarded to F.A.M. D.V.N. was co-financed from the European Social Fund through Sectorial Operational Program Human Resources Develo
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br Conclusion br Conflicts of interest
2023-09-23
Conclusion Conflicts of interest Introduction Alzheimer’s disease is the most common neurodegenerative condition known to cause dementia (Ferri et al., 2005). Alzheimer’s dementia typically presents with initial recent episodic memory deficits, word finding difficulty and later with apraxia
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br Conclusion br Conflicts of interest
2023-09-23
Conclusion Conflicts of interest Introduction Alzheimer’s disease is the most common neurodegenerative condition known to cause dementia (Ferri et al., 2005). Alzheimer’s dementia typically presents with initial recent episodic memory deficits, word finding difficulty and later with apraxia
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Introduction A defining feature of cancer
2023-09-23
Introduction A defining feature of cancer cells is disruption of the normal controls of the cell cycle; a tumor suppressor or inhibitor may act by restricting progression of the cell cycle. P27 (also known as cyclin-dependent kinase inhibitor 1B, P27, or Kip1) is a putative cell-cycle inhibitor pro
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One study has demonstrated that PUFA reduced both cholestero
2023-09-22
One study has demonstrated that ω-3 PUFA reduced both cholesterol and caveolin-1 (a marker of raft), thereby displacing raft-associated signaling molecules from lipid raft [36]. Additionally, DHA treatment decreased the amount of lipid raft in the cell surface and displaced several lipid raft-associ
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The results also showed that the A receptor http
2023-09-22
The results also showed that the A3 receptor agonist increased the phosphorylated levels of Akt, leading to activation of the PI3K/Akt pathway. A3 Concanamycin A stimulation has protective effects against RGC death following ischemia-reperfusion, glutamate toxicity, and optic nerve transection model
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The present study indicates elevated ATX activity as a
2023-09-22
The present study indicates elevated ATX activity as a highly sensitive and specific biomarker to differentiate ICP from other pregnancy-related liver disorders or pruritic dermatoses. In VUF 10166 to the current gold standard for diagnosis, total fasting serum bile salt levels, ATX appeared as a ve
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br Introduction Cadmium is a major
2023-09-22
Introduction Cadmium is a major component of heavy metal pollution. Phytoremediation is considered to be the more effective method for recovering contaminated soil [[1], [2], [3], [4]] via cadmium absorption, transport, and accumulation. Several cadmium-associated proteins have previously been we
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