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hcv protease inhibitor br Contributors br Funding br Conflic
2019-04-26
Contributors Funding Conflict of interest Patient consent Ethics approval Acknowledgment Introduction Perforation of a cardiac chamber has been reported as a relatively rare complication of pacemaker implantation; in particular, attachment of the active-fixation atrial lead to t
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A major challenge to the scale up of provider initiated
2019-04-26
A major challenge to the scale-up of provider-initiated HIV testing and counselling is the time needed to provide detailed counselling when faced with inadequate staffing and other competing health-care priorities. Therefore, the Ugandan Ministry of Health developed a brief HIV counselling protocol
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Introduction Friedenstein was the first
2019-04-26
Introduction Friedenstein was the first person to describe the isolation of clonogenic, proliferating fibroblastic MSCs from rat bone marrow (BM). And they showed that colony-forming unit fibroblasts (CFU-Fs) derived stromal pilocarpine hydrochloride can serve as feeder layers for the culture of he
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Different ideas however emerged in the s and s
2019-04-26
Different ideas, however, emerged in the 1960s and 1970s in the minds of computational biologists interested in the theory of wave propagation in excitable media. Based on chemical [17] and numerical experiments, [18] scientists in the Soviet Union and the USA began to suggest that fibrillation was
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The so called driver hypothesis has been posited in
2019-04-26
The so-called driver fasudil has been posited in the recent years. Optical mapping studies in isolated sheep hearts have suggested that at least some cases of AF can be maintained by high-frequency reentrant sources (rotors), usually located in the posterior LA, which result in spatially distribute
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br Una pol mica entre traductores Probablemente mientras tra
2019-04-25
Una polémica entre traductores Probablemente, mientras traducía China en armas, Owen leyó y reseñó la traducción de El diablo en el cuerpo de Raymond Radiguet, hecha por Ángel Samblancat. Aun cuando aquél se dedica cam kinase perorar sobre la vida y la obra de Radiguet, a partir de los testimonio
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br It s that time of year again when
2019-04-25
It\'s that time of year again when we ask readers to submit photographs for our annual Highlights photography competition. We are looking for striking images that arrest our attention about any topic in medicine, from global health to clinical medicine, from the individual person to populations. A
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One year after her initial diagnosis the patient
2019-04-25
One year after her initial diagnosis, the patient presented back for the abrupt onset of symmetrical bilateral lower-limb weakness and numbness. The patient did not report other symptoms or history of trauma. Clinical examination revealed a healthy person except for a symmetrical proximal and distal
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br On March the Indian Government banned around irrational
2019-04-25
On March 10, 2016, the Indian Government banned around 330 “irrational” fixed-dose combination drugs (FDCs) with immediate effect. FDCs are products that rilpivirine contain two or more active drugs in a fixed-dose ratio, and are useful for minimising pill burden and lowering cost. However, FDCs s
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Many previous studies have reported that activation of
2019-04-25
Many previous studies have reported that activation of p38 induces cell death of hippocampal neurons rather than cell survival by using p38-specific inhibitors [18,[25], [26], [27], [28], [29], [30], [31], [32]]. A plausible explanation for this discrepancy is that we used both a cell-permeable p38
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br Discussion In the present report we describe
2019-04-25
Discussion In the present report, we describe a technique for the XMU-MP-1 of a 6.0 Fr active fixation atrial lead in the inferior IAS using a 9.0 Fr GC. Previous studies have indicated that inferior IAS pacing significantly reduces paroxysmal AF burden and recurrence and slows the progression t
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Roughly years have gone by since the identification of
2019-04-25
Roughly 15 years have gone by since the identification of the main characters involved in the interplay of the RANK–RANKL system. This gave rise to the race for elucidating their biological role . In those years, in vivo silencing experiments for both Receptor Activator of Nuclear Factor κ B (RANK)
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There are important methodological issues
2019-04-25
There are important methodological issues affecting the study of child mortality inequalities on the basis of survey data. McKinnon and colleagues relied on rigorous analytical tools to study these changes, and in some aspects—for example the graphical display of the statistical significance of chan
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Un ciclo diferente y mucho m s profundo de transformaciones
2019-04-25
Un ciclo diferente y mucho más profundo de transformaciones se inicia con el proceso constitucional en Bolivia y Ecuador. Bolivia se “re-funda” en 2009 y se proclama Estado Unitario Social de Derecho Plurinacional Comunitario. El capítulo cuarto sobre los derechos de las naciones y pueblos indígenas
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GP ablation has been regarded as
2019-04-24
GP ablation has been regarded as a vagal denervation procedure that reduces the vagal tone in the atria and the vulnerability to AF. However, it is unclear how much vagal effect on the atrium is attenuated and how much of the atrium is denervated after the ablation. According to the GP mapping by Mc
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